Potential benefits
- • Increase tear retention
- • Reduce symptoms for selected aqueous-deficient dry eye patients
- • Provide an alternative form of temporary tear-drainage occlusion
Lacrifill for dry eye
A cross-linked hyaluronic acid canalicular gel intended to temporarily block tear drainage.
What is Lacrifill?
Lacrifill is placed into the tear-drainage canaliculus to reduce tear outflow. Its goal is similar to punctal occlusion: keeping more tears on the eye surface.
How it works
A trained clinician inserts the gel through the punctal opening into the canaliculus during an office procedure.
Risks and limitations
- • Excess tearing, irritation, inflammation, infection, or drainage-system complications may occur
- • Retaining tears may be unhelpful when significant ocular-surface inflammation is untreated
- • Availability and regulatory status vary by country
Questions to ask a clinic
Why is canalicular occlusion appropriate before controlling inflammation?
How does this option compare with punctal plugs in my case?
What findings from my eye examination support this treatment?
What alternatives should I consider first?
How will we measure whether it is helping?
What will the total treatment and follow-up cost be?
Find local care
Find clinics offering Lacrifill near you
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Related treatments
References
- Lacrifill Canalicular Gel device listing — U.S. Food and Drug Administration
- TFOS DEWS II Management and Therapy Report — The Ocular Surface
Last reviewed June 11, 2026. This page is educational and does not provide medical advice. Discuss diagnosis, suitability, risks, and alternatives with a qualified eye-care professional.